Murine hepatitis virus (MHV) genome and nsp5 protease structure and activity. (A) The MHV genome consists of 7 genes. The replicase gene encodes 16 nonstructural proteins that are processed by viral papain-like protease 1 (PLP1), PLP2, and nsp5 protease. nsp5 is responsible for 11 processing events between nsp's 4 and 16.
Abstract. Phosphodiesterase 4D (PDE4D) has recently been implicated as a proliferation-promoting factor in prostate cancer and is overexpressed in human prostate carcinoma. However, the effects of PDE4D inhibition using pharmacologic inhibitors have not been examined in prostate cancer. These studies examined the effects of selective PDE4D inhibitors, NVP-ABE171 and cilomilast, as anti
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The qualitative and quantitative determination of chlorinated pesticides was performed using a gas chromatography Fisons Instruments GC 8000 series, electron capture detector 63 Ni-ECD (GC-ECD). The column for GC-ECD was a HP-5-MS capillary (30 m ×0.25 mm i.d., 0.25 μm film thickness).Helium 5.0 was used as carrier gas for the system (75 Psi, 1 ml min −1).
Vay Tiền Nhanh.
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